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. 2019 Apr 15;100(6):1498–1506. doi: 10.4269/ajtmh.18-0922

Table 3.

Linear regression models with VO2max as the outcome, stratified by altitude

Unadjusted analysis Multivariable-adjusted analysis
Coefficient 95% CI P- value Coefficient 95% CI P-value
Schistosoma mansoni egg patent infection*
 Low altitude 1.299 2.389 0.208 0.020 3.962 6.556 1.368 0.004
 High altitude −0.971 −2.712 0.770 0.271 0.452 −5.102 6.007 0.866
Fecal occult blood
 Low altitude −0.610 −1.349 0.128 0.104 −0.226 −1.362 0.911 0.690
 High altitude 0.592 −0.333 1.518 0.205 0.694 −1.094 2.482 0.424
Malaria†
 Low altitude −0.938 −2.320 0.444 0.182 −2.121 −4.390 0.148 0.066
 High altitude 2.832 0.494 5.170 0.019 5.524 0.084 10.964 0.047
Stunting‡
 Low altitude −0.448 −1.749 0.853 0.498 −0.126 −2.715 2.463 0.922
 High altitude −0.719 −2.875 1.438 0.510 −0.842 −6.230 4.547 0.746
Anemia§
 Low altitude −0.924 −2.145 0.297 0.137 0.891 −1.418 3.201 0.440
 High altitude −0.326 −2.076 1.424 0.711 −1.834 −5.384 1.717 0.291

AIC = Akaike’s information criterion. Statistically significant differences (P ≤ 0.05) indicated in bold.

* As per dual Kato–Katz examination.

† As per malaria rapid diagnostic testing.

‡ According to validated stunting charts based on height-for-age Z-score ≤ 2 SD below mean.35

§ As per standardized hemoglobin cutoffs for age: < 11.5 g dL−1 (5–11 years) and < 12.0 g dL−1 (12–14 years). Hemoglobin adjusted for altitude.39 For multivariable-adjusted analysis, low altitude: n = 45. P-value = 0.022. R2 = 0.277. Adjusted R2 = 0.184. AIC = 246.900. High altitude: n = 23. P-value = 0.202. R2 = 0.326. Adjusted R2 = 0.128. AIC = 125.111.