Fig. 6.

Validation of mitochondrial hits CoxIV, ATP5A, NDUFS3 and SDHB obtained from the LG proteome. A, Sub-categories significantly enriched under the category “metabolism” in Asrij OV LGs. B, Graphs showing average fluorescence intensity levels of CoxIV, ATP5A, NDUFS3 and SDHB across primary, secondary and tertiary LG lobes. Genotypes are as indicated (n>7 per genotype). Error bars represent standard error of mean and “ns” indicates statistically non-significant difference. * p < 0.05, ** p < 0.01 and *** p < 0.001. C, Comparison of proteome-obtained and experimentally validated expression levels of LG CoxIV, ATP5A, NDUFS3 and SDHB.