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Accuracy and optimal threshold value of TT-TG distance to determine PFI risk. Accuracy is reflected by the AUC. The optimal threshold, IU, is obtained from the equation IU(c) = ( | sensitivity(c) – AUC | + | specificity(c) – AUC | ) where c denotes cut points on the ROC curve; mathematically, the cut point minimizing the IU(c) function and the | sensitivity(c) – specificity(c) | difference is designated as an optimal value [76].
