Skip to main content
. 2019 Apr 30;34(6):1106–1116. doi: 10.1093/humrep/dez041

Figure 4.

Figure 4

Metronidazole treatment reduces endometriotic lesion growth. (A–C) Representative gross images (A), volumes (B) and masses (C) of ectopic endometriotic lesions from the indicated treatment groups; (n = 5). (D) Representative Hematoxylin and Eosin-stained cross-section images of ectopic lesions from the indicated treatment groups; n = 5. Scale bars represent 200 μm (upper panel) or 500 μm (lower panel). (E) Quantification of IL-1β concentration in peritoneal fluid from the indicated treatment groups. (F) Representative cross-sectional images of ectopic lesions stained for Iba1; graph on the right shows the number of positively stained cells counted in at least five different areas in ectopic lesions and plotted as percent positive cells relative to total cells. ‘E’, ‘G’ and ‘S’ denote epithelia, glands and stroma, respectively. Data are presented as mean ± SE; (n = 5). *P < 0.05, ***P < 0.001, ****P < 0.0001, and ns, non-significant.