Table 2.
Diagnostic performance of APTw-MRI and DWI and/or DCE-MRI for malignant tumors.
| Cut-off value | Sensitivity (%) | Specificity (%) | |
|---|---|---|---|
| Mean APTw-signal | 1.90% | 100 | 78.3 |
| Maximum APTw-signal | 7.19% | 93.3 | 87.0 |
| Median APTw-signal | 2.42% | 80.0 | 91.3 |
| Skewness | 0.365 | 93.3 | 78.3 |
| Kurtosis | 0.270 | 86.7 | 56.5 |
| ADC alone | 1.44 × 10−3 mm2/sec | 100 | 60.9 |
| TIC alone | Type C | 80.0 | 60.9 |
| ADC and TIC | Ref.* | 73.3 | 82.6 |
Note, APTw-MRI = amide proton transfer-weighted MRI, APTw-signal = amide proton transfer-weighted signal, DCE-MRI = dynamic contrast-enhanced magnetic resonance imaging, TIC = time-intensity curve.
*Ref, Refer to the subsection of “DWI and DCE-MRI analysis” of the “Materials and Methods” section.