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. 2019 May 31;10:610. doi: 10.3389/fphar.2019.00610

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Copyright © 2019 Zhang, Chen, Deng, Zhang, Sun, Wang, Yang, Lv, Han and Xie

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The left ventricular opacification (LVO) in rats. (A) The representative LVO images of nanobubbles and microbubbles. (B) Grayscale intensity comparison between nanobubbles and microbubbles at the same time point.