Table 2.
Candidate | FGF20 fold increase | SEM | P value | |
---|---|---|---|---|
dimethadione | 4.40 | 0.87 | 0.0095 | ** |
trazodone | 2.68 | 0.23 | 0.0024 | ** |
salbutamol | 2.69 | 0.13 | 0.0002 | *** |
atenolol | 2.92 | 0.49 | 0.013 | * |
propranolol | 4.29 | 0.50 | 0.002 | ** |
levonorgestrel | 3.38 | 1.03 | 0.067 | |
sitosterol | 2.19 | 0.93 | 0.189 | |
clonidine | 2.99 | 0.71 | 0.013 | * |
luteolin | 2.06 | 0.32 | 0.019 | * |
torsemide | 3.92 | 1.20 | 0.036 | * |
estriol | 2.09 | 0.41 | 0.05 | |
triflusal | 3.72 | 0.78 | 0.003 | ** |
ethaverine | 3.65 | 0.66 | 0.013 | * |
betamethasone | 2.29 | 0.81 | 0.08 | |
testosterone | 2.57 | 0.48 | 0.016 | * |
equilin | 2.39 | 0.76 | 0.16 |
Drugs in bold were taken forward into ventral mesencephalic primary culture studies. P value obtained by Student’s t-test analysis between drug treatment and individual vehicle controls. *, ** and *** are P values < 0.05, <0.01 and <0.001, respectively.