Table 1.
Number of papers reporting the results of a drug development study with molecular imaging by therapeutic area and publication year
| Therapeutic area | Publication year* | |||||||
|---|---|---|---|---|---|---|---|---|
| 1990–1994 | 1995–1999 | 2000–2004 | 2005–2009 | 2010–2014 | 2015 | Total | p value | |
| Oncology | 0 (0.0) | 0 (0.0) | 16 (59.3) | 14 (32.6) | 60 (68.2) | 9 (52.9) | 99 (47.6) | |
| CNS | 9 (75.0) | 18 (85.7) | 5 (18.5) | 19 (44.2) | 21 (23.9) | 4 (23.4) | 76 (36.5) | |
| Cardiovascular | 1 (8.3) | 1 (4.8) | 5 (18.5) | 7 (16.3) | 5 (5.7) | 3 (17.6) | 22 (10.6) | |
| Gastrointestinal | 0 (0.0) | 0 (0.0) | 1 (3.7) | 1 (2.3) | 1 (1.1) | 0 (0.0) | 3 (1.4) | |
| Antibiotics | 2 (16.7) | 1(4.8) | 0 (0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 3 (1.4) | |
| Others | 0 (0) | 1 (4.8) | 0 (0) | 2 (4.7) | 1 (1.1) | 1(5.9) | 5 (2.4) | |
| Total | 12 (100) | 21 (100) | 27 (100) | 43 (100) | 88 (100) | 17 (100) | 208 (100) | <0.0001 |
Frequency (column percentage) is shown
CNS, central nervous system
*5-year epoch except for 2015, for which 1-year data were presented