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Irradiation reduced neural stem/progenitor cell proliferation in the cerebellum. (A) Representative pictures showing Ki-67-labeled cells in the cerebellum. (B) Quantitative analysis of Ki-67–labeled cells in the EGL of the cerebellar lobule. (C) Bar graphs showing mRNA level of Ki-67, DCX, and SOX2 in the cerebellum. n = 7/group for immunohistochemistry staining; n = 5/group for the qRT-PCR assays. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.
