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. 2019 Jun 4;17:100089. doi: 10.1016/j.bdq.2019.100089

Table 1.

Overview of applied strategies to purify small extracellular vesicles from urine.

Purification type: Based on: Manufacturer:
A Spin column chromatography Urine Exosome Purification and RNA Isolation Midi Kit (Norgen Biotek, Norway)
B Immunoaffinity Exosome Isolation Kit Pan, human (Miltenyi Biotec, Germany)
C Membrane affinity exoRNeasy Serum/Plasma Midi Kit (Qiagen, Germany)
D Precipitation miRCURY Exosome Isolation Kit – Cells, urine and CSF (Exiqon, Denmark)
E Ultracentrifugation with density gradient Optima LE-80 K (Beckman Coulter, USA) and OptiPrep (Merck, Germany)