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. 2019 Feb 10;27(6):1166–1182. doi: 10.1016/j.ymthe.2019.02.002

Figure 2.

Figure 2

miR-577 Promotes GC Metastasis In Vitro and In Vivo

(A and B) Effect of miR-577 AgomiR or AntagomiR on the migration and invasiveness of MGC803 (A) and MKN45 (B) cells based on Transwell assays. **p < 0.01. Magnification, 100×. (C) Fluorescence images of lung homing potential of miR-577-expressing or silencing group mice and control group mice. (D) Luciferase signals of lung metastasis nudes in miR-577-expressing or silencing group mice and control group mice; the data were expressed as mean ± SD. **p < 0.01. (E) Kaplan–Meier survival curves and univariate analyses (log rank) for the mice with miR-577-expressing or silencing cells versus control cells were performed. (F) Representative image of H&E staining of lung metastasis in miR-577-expressing or silencing group mice and control group mice.