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. 2019 Feb 10;27(6):1166–1182. doi: 10.1016/j.ymthe.2019.02.002

Table 1.

Univariate and Multivariate Analyses of Individual Parameters for Correlations with Overall Survival Rate: Cox Proportional Hazards Model

Variables Univariate
Multivariate
HR CI (95%) p Value HR CI (95%) p Value
Age (≥55/< 55) 0.574 0.434–0.759 0.000* 0.738 0.547–0.995 0.046*
Gender (male/female) 0.985 0.693–1.401 0.308 1.137 0.781–1.655 0.504
T classification (III + IV/I + II) 3.935 2.041–7.585 0.000* 3.172 1.607–3.552 0.001*
N classification (N1–3/N0) 1.538 1.027–2.302 0.037* 1.44 0.953–2.176 0.083
M classification (M1/M0) 1.841 1.275–2.657 0.01* 1.496 0.979–2.285 0.062
Differentiation (moderate/well) 0.895 0.488–1.640 0.719 1.207 0.644–2.262 0.558
Differentiation (poor/well) 1.094 0.614–1.949 0.76 1.67 0.905–3.085 0.101
miR-577 expression (high/low) 2.473 1.707–3.580 0.000* 2.389 1.607–3.552 0.000*

HR; hazard ratio; CI; confidence interval. *Statistically significant (p < 0.05).