Table 1.

Overview of Conducted Simulations

System	Purpose	Replicas per Temperature	Length	Temperatures	Total Number
DPPCgf	Gel-fluid interface	1	100 ns	280/360 K	1
DPPCgf	Determination of Tm	1	100 ns	314–330 K (ΔT = 2 K)	9
DPPCgf	Electroporation	3 × 10a	≤100 nsb	321 K (= Tm)	30
DPPCgf	Pore closure	1	100 ns	321 K (= Tm)	1
DPPCf	Nanodomain formation	1	500 ns	322, 326, 330, 335, 340 K	5
${\text{DPPC}}_s^f$	Electroporation	3 × 10a	≤100 nsb	322, 330, 335, 340 K	120
DPPCf	Electroporation	3 × 10a	≤100 nsb	322, 335 K	60

^a10 replica simulations were performed each starting from three different configurations.

^bSimulations were conducted until 100 ns or stopped after an electropore formed.