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. 2019 Jun 5;39(23):4606–4623. doi: 10.1523/JNEUROSCI.3069-18.2019

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Figure 4. — Enhancement of EET signaling in the mPFC produces antidepressant-like effects. A, Effect of mPFC infusion of TPPU (1 μm), TUCB (0.1 μm), 14,15-EET (1 μg), or vehicle on immobility in the FST. B, mPFC infusions of TPPU (1 μm), TUCB (0.1 μm), or 14,15-EET (1 μg) did not affect locomotor activity compared with the controls. C, D, Hippocampal infusions of TPPU (1 μm), TUCB (0.1 μm), or 14,15-EET (1 μg) could not induce antidepressant-like effects in the FST. Data are mean ± SEM. *p < 0.05.