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. 2019 Jun 5;39(23):4606–4623. doi: 10.1523/JNEUROSCI.3069-18.2019

Table 2.

Brain-regional EET levels in CSDS paradigma

Structure Group EETs (ng/g) 5,6-EET (ng/g) 8,9-EET (ng/g) 11,12-EET (ng/g) 14,15-EET (ng/g)
mPFC Control 5.089 ± 0.225 1.710 ± 0.185 0.604 ± 0.187 0.946 ± 0.117 1.829 ± 0.097
Susceptible 3.349 ± 0.419* 1.219 ± 0.315 0.453 ± 0.116 0.575 ± 0.099 1.101 ± 0.077**
Resilient 4.923 ± 0.649 1.813 ± 0.456 0.830 ± 0.201 0.877 ± 0.156 1.404 ± 0.137
Hippocampus Control 4.126 ± 0.352 1.448 ± 0.280 0.694 ± 0.159 0.905 ± 0.132 1.078 ± 0.121
Susceptible 3.642 ± 0.150 1.130 ± 0.233 0.748 ± 0.144 0.696 ± 0.140 1.067 ± 0.133
Resilient 4.217 ± 0.407 1.295 ± 0.300 1.077 ± 0.254 0.702 ± 0.071 1.142 ± 0.102
NAc Control 5.069 ± 0.499 1.764 ± 0.274 0.776 ± 0.294 0.983 ± 0.094 1.546 ± 0.245
Susceptible 4.928 ± 0.584 1.739 ± 0.399 0.871 ± 0.229 0.937 ± 0.264 1.380 ± 0.151
Resilient 5.645 ± 0.765 1.940 ± 0.281 0.937 ± 0.237 1.142 ± 0.305 1.627 ± 0.182
Striatum Control 3.151 ± 0.250 0.932 ± 0.232 0.663 ± 0.137 0.548 ± 0.107 1.008 ± 0.095
Susceptible 2.845 ± 0.245 0.931 ± 0.171 0.269 ± 0.099 0.452 ± 0.108 1.193 ± 0.091
Resilient 3.348 ± 0.330 1.192 ± 0.258 0.571 ± 0.154 0.612 ± 0.128 0.974 ± 0.131
Cerebral cortex (without the mPFC) Control 6.137 ± 0.511 2.084 ± 0.231 1.396 ± 0.334 0.941 ± 0.167 1.715 ± 0.262
Susceptible 5.106 ± 0.442 1.463 ± 0.190 0.518 ± 0.212* 1.368 ± 0.133 1.756 ± 0.292
Resilient 6.845 ± 0.606 2.548 ± 0.430 1.302 ± 0.247 1.254 ± 0.122 1.741 ± 0.122

aEET levels detected in the mPFC, hippocampus, NAc, striatum, and cerebral cortex when mice were killed 24 h after the CSDS. Data are mean ± SEM; n = 8–10.

*p < 0.05 compared with control (one-way ANOVA);

**p < 0.001 compared with control (one-way ANOVA).