Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jul 2;40(22):1771–1777. doi: 10.1093/eurheartj/ehy365

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018. Published by Oxford University Press on behalf of the European Society of Cardiology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Influence of ischemia/reperfusion injury and cardiovascular risk factors on cardiotoxic effects of drugs. Hidden cardiotoxicity of a drug is revealed if the drug inhibits cell survival signalling or activates deleterious cell signalling induced by cardiac diseases especially ischemia/reperfusion injury and/or its major risk factors including their comedications. APD, action potential duration; HERG, human ether-a-go-go-related gene potassium channel; LQTs, long QT syndromes; SCD, sudden cardiac death.