Table 2F.

Multiple linear regression analysis of variables that showed significant association with ADP.

Combined group analysis
	β	P
HN (pg/ml)	0.088	0.314
Weight (kg)	−0.162	0.042
HbA1C %	−0.231	0.034
TG (mmol/L)	0.057	0.834
HDL (mmol/L)	0.067	0.564
ALT (U/L)	−0.116	0.113
TG/HDL	−0.168	0.571
TCH/HDL	−0.044	0.658

Spearman Rank correlation analysis was used for calculation of associations between HN (2A), MOTS-c (2C), ADP (2E), and clinical variables. If individual bivariate correlations achieved statistical significance those variables were included for multivariate linear regression analysis to test the joint effect of these parameters on HN (2B), MOTS-c (2D), and ADP (2F). Age, weight, HbA1c, glycated hemoglobin; MOTS-c, mitochondrial open reading frame of the 12S rRNA type-c; HN, humanin; ADP, adiponectin; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; ALT, alanine aminotransferase; TCH, total cholesterol; HDL, high density lipoprotein; LDL, low density lipoprotein; VLDL, very low density lipoprotein; TG, triglycerides; R, Spearman rank correlation coefficient; β, standardized linear regression beta coefficients; P < 0.05 was considered as significant.