Table 3.
Effects of antidiabetic medications on serum HN, MOTS-c and ADP levels.
| Diabetes Treatment | N = | HN (pg/ml) Mean ± SD | MOT-c (pg/ml) Mean ± SD | ADP (μg/ml) Mean ± SD | p |
|---|---|---|---|---|---|
| Newly diagnosed diabetes (diet and lifestyle?) | 11 | 431.1 ± 203.7 | 172.3 ± 89.9 | 7.6 ± 3.5 | |
| Metformin | 32 | 470.1 ±256.4 | 162.9 ± 107.6 | 7.9 ± 5.2 | NS |
| Insulin | 24 | 508.9 ± 343.1 | 156.8 ± 85.9 | 9.9 ± 6.7 | NS |
| Any oral hypoglycemic agents + metformin | 30 | 341.2 ± 219.4 | 170.7 ± 111.0 | 7.3 ± 7.2 | NS |
| Insulin + any oral hypoglycemic agents | 27 | 432.8 ± 203.7 | 202.7 ± 140.9 | 6.6 ± 4.1 | NS |
Effects of hypoglycemic agents on circulating HN, MOTS-c, and ADP. Data are represented as Mean ±SD. Group comparision was done by one-way ANOVA analysis with post-hoc Bonferroni correction.