Skip to main content
. 2019 Apr 11;27(6):1183–1194. doi: 10.1016/j.ymthe.2019.03.020

Figure 5.

Figure 5

Therapeutic Delivery of miR-29b Enhances Radiosensitivity in Cervical Cancer

(A) Systemic delivery of nanoparticle (R11-SSPEI/miR-29b or R11-SSPEI/Scr) leads to accumulation of miR-29b mimics in tumor after subcutaneous injection in mice. Two mice per treatment group were sacrificed 2 h after injections, and the tissues and transplanted tumors were harvested for total RNA extraction and evaluation of miR-29b levels. (B) Therapeutic delivery of miR-29b significantly sensitized lung cancer cells to radiation (XRT). The effect of R11-SSPEI/miR-29b on radioresponse of HeLa-R cells was measured by a tumor growth delay assay.