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. Author manuscript; available in PMC: 2020 Jun 7.
Published in final edited form as: Lab Chip. 2019 May 13;19(11):2019–2037. doi: 10.1039/c8lc01037d

Figure 3.

Figure 3.

a) An overview of the most common extrusion bioprinting approaches; reprinted with permission from Malda et al. 201377. b) Schematic of the theoretical modeling, with an inset showing a realistic velocity profile inside the nozzle. c) Theoretical simulation of normalized strand diameter (d/D) versus normalized viscosity (K¯: K divided by water viscosity) and theoretical simulation of normalized strand diameter (d/D) versus nozzle moving speed (V) for four power-law constant values. d) Numerical simulation of normalized strand diameter (d/D) versus normalized speed (V¯= V divided by inlet velocity of bioink ~ Vmax/2; for n=0.3 and K¯=100; circle; red) and normalized viscosity (K¯for n=0.3 and V¯=3; square; blue), where 3D perspectives of extruded bioinks are shown for the extreme case. e) 3D perspective view of bioink extruded for four viscosity ratios (K¯) and n=0.3. f) 3D perspective view of bioink extruded for four velocity ratios (V¯) and n=0.3.