. Author manuscript; available in PMC: 2019 Jun 7.

Published in final edited form as: J Invest Dermatol. 2008 Mar 6;128(8):1981–1990. doi: 10.1038/jid.2008.34

Table 1.

TGF-α- and insulin-regulated total and common genes

	Upregulated genes			Downregulated genes
Growth factor	30 min	60 min	120 min	30 min	60 min	120 min
TGF-α	71	174	209	46	41	74
Insulin	75	109	42	28	47	39
Shared genes	25	58	13	1	15	3
%	35 (TGF-α) 33 (ins.)	33 (TGF-α) 53 (ins.)	6 (TGF-α) 31 (ins.)	2 (TGF-α) 4 (ins.)	37 (TGF-α) 32 (ins.)	4 (TGF-α) 8 (ins.)

ins., insulin; TGF, transforming growth factor.

The result of DNA microarray analysis is shown, on the basis of the significance of gene expression (P<0.05) in the probe-based analysis calculated by using SScore software. The numbers shown from TGF-α- or insulin-stimulated cells for the indicated times are the total numbers of up- or downregulated genes. Among them, the commonly up- or downregulated genes are referred to as “shared genes”. The percentage of shared genes over the total number of genes regulated under TGF-α or insulin treatment is shown as “%”.