Figure 2. Predictive results: CRIM status vs. GAA-iTEM.
Using an GAA-iTEM score threshold of +10 (right) results in correct predictions for 92% of patients with GAA-iTEM scores > 10 and 80% of patients with GAA-iTEM scores <10 whereas using CRIM status as a predictor of High ADA response to ERT (left) only results in correct predictions for 55% of CRIM positive patients.