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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Mol Genet Metab. 2018 Nov 2;125(4):338–344. doi: 10.1016/j.ymgme.2018.10.007

Figure 3.

Figure 3.

(a) NO production was significantly lower in GLA-deficient cell lines, 5, 12, and 14, when compared to the WT control 17. n=18. (b) GLA-deficient cells have less eNOS protein expression. A representative Western blot from CRISPR/Cas9 clonal cell lines is shown. GLA-deficiency causes a decrease in eNOS expression in clone 12, but is not statistically significant (p=0.08). Clone 2, n=3; clones 5, 12, and 14, n=4; clone 17(WT), n=6. **P<0.01, ****P<0.0001 compared to 17(WT)