Fig. 4.

Liraglutide affects body weight and upregulates GLP-1R in the cartilage tissues of the knee OA rat mode. a Body weight of rats in the “OA”, “OA + saline” and “OA + liraglutide” groups at 0 day, 7th day, 14th day, 21st day and 28th day after treatment with liraglutide or saline (n = 5 per group). b Representative Western blots and quantification data of GLP-1R in the “OA”, “OA + saline” and “OA + liraglutide” groups (n = 5 per group). c Representative images (100 × and 200×) of IHC staining and corresponding quantification of GLP-1R levels in the “OA”, “OA + saline”, and the “OA + liraglutide” groups (n = 5 per group). * indicates P < 0.05 compared with the “OA + saline” group