Table 1.
Olanzapine | Risperidone | Haloperidol | ||
N = 2128 | N = 417 | N = 112 | p-value | |
Age (years) | 35.6 ± 11.7 | 34.4 ± 11.2 | 34.3 ± 10.4 | NS |
Sex (% females) | 36.3 | 34.1 | 39.3 | NS |
Disease Duration (years) | 11.1 ± 9.6 | 10.3 ± 9.0 | 9.5 ± 9.5 | NS |
Schizophrenia subtype | ||||
(%) | ||||
• Paranoid | 64.7 | 65.1 | 72.3 | |
• Undifferentiated | 13.6 | 13.7 | 11.6 | |
• Residual | 12.8 | 11.8 | 5.4 | NS |
• Disorganized | 8.4 | 8.4 | 10.7 | |
• Catatonic | 0.5 | 1.0 | 0.0 | |
Baseline CGI-S | 4.66 ± 0.91,2 | 4.53 ± 0.9 | 4.9 ± 0.91 | 1 p < 0.005 (RIS) |
2 p < 0.050 (HAL) | ||||
Baseline GAF | 44.9 ± 14.83,4 | 46.7 ± 14.6 | 40.7 ± 16.2 | 3 p < 0.050 (RIS) |
4 p <0.005 (HAL) |