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. 2019 Jun 7;18:103. doi: 10.1186/s12934-019-1151-8

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The specific antibody in mice induced by recombinant B. subtilis-gCa and B. subtilis-gDa. a Detection of anti-PRV IgG antibody in serum from immunized mice by indirect ELISA. *P < 0.05, **P < 0.01 compared to B. subtilis-PRV. ^#P < 0.05, ^##P < 0.01 compared to B. subtilis-gCa. b The anti-PRV specific mucosal SIgA antibody in broncheoalveolar lavage (BAL) by indirect ELISA. **P < 0.01. c The anti-PRV specific mucosal SIgA antibody in vagina by indirect ELISA. Data were expressed as the mean ± SD. **P < 0.01