Table 4A.

Univariate analysis of clinicopathological findings and miRNA expression patterns as predictors of metachronous metastasis in clear cell renal cell carcinoma.

Risk factor	Hazard ratio	95% CI	P-value
Fuhrman grade
3 vs. 2	2.918	1.254–6.939	0.013*
Necrosis
Presence vs. absence	3.002	1.283–7.036	0.012*
Venous invasion
Positive vs. negative	2.872	1.083–6.919	0.035*
pT stagea			0.029
pT2 vs. pT1	3.198	1.084–8.647	0.036*
pT3 vs. pT1	3.134	1.053–8.565	0.040*
pT3 vs. pT2	0.979	0.301–3.186	0.972
miRNA expression subgroupb			0.013
2 vs. 1	0.673	0.146–2.357	0.552
3 vs. 1	3.198	1.261–8.598	0.014*
3 vs. 2	4.746	1.476–21.041	0.007*

Overall significance of

^aP = 0.029 and

^bP = 0.013. CI, confidence interval.

^*P < 0.05.