Table 6.
Prediction of metachronous metastasis based on the cutoff expression levels of specific microRNAs in patients with clear cell renal cell carcinoma: sensitivity, specificity, positive predictive value and negative predictive value.
| microRNA | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|
| miRNA-155-5p | 63.6 | 55.4 | 29.8 | 83.7 |
| miRNA-122-5p | 100.0 | 17.6 | 26.5 | 100.0 |
| miRNA-21-5p | 63.6 | 51.4 | 28.0 | 82.6 |
| miRNA-185-3p | 9.1 | 89.2 | 20.0 | 76.7 |
| miRNA-106a-5p | 45.5 | 39.2 | 18.2 | 70.7 |
| miRNA-106b-3p | 27.3 | 64.9 | 18.8 | 75.0 |
| miRNA-34b-3p | 77.3 | 31.1 | 25.0 | 82.1 |
| miRNA-210-3p | 77.3 | 32.4 | 25.4 | 82.8 |
| miRNA-141-3p | 72.7 | 20.3 | 21.3 | 71.4 |
| miRNA-200c-3p | 9.1 | 82.4 | 13.3 | 75.3 |
| miRNA-135a-5p | 45.5 | 81.1 | 41.7 | 83.3 |
| miRNA-30a-5p | 59.1 | 52.7 | 27.1 | 81.3 |
| miRNA-218-5p | 50.0 | 74.3 | 36.7 | 83.3 |
| miRNA-429 | 36.4 | 75.7 | 30.8 | 80.0 |
| miRNA-200a-3p | 50.0 | 48.6 | 22.4 | 76.6 |
| miRNA-200b-3p | 90.9 | 18.9 | 25.0 | 87.5 |
PPV, positive predictive value; NPV, negative predictive value. miR, microRNA.