Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Molecular interactions of synthetic oligonucleotides. Synthetic oligonucleotides, such as ASOs, can mediate both specific and nonspecific molecular interactions. Their multivalent negative charge, base-pairing potential, and sequence motifs can be responsible for various forms of nonspecific interactions and off-target effects. ASOs, antisense oligonucleotides.
