Table 6.
Subgroup analyses for interaction model including disorder and onset group.
| p-values of subgroup-analyses for subgroups 1-3 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Interaction | n | s | o | g | SE | p-value | 1 vs. 2 | 2 vs. 3 | 1 vs. 3 | τ |
| 0.143 | ||||||||||
| MDD | ||||||||||
| 1 Late-onset | 10 | 10 | 21 | 0.516 | 0.067 | <0.001 | <0.001 | – | – | |
| 2 Early-onset | 8 | 8 | 20 | −0.081 | 0.071 | 0.255 | – | 0.003 | – | |
| 3 Late-life | 34 | 38 | 89 | 0.159 | 0.038 | <0.001 | – | – | <0.001 | |
| BD | ||||||||||
| 1 Late-onset | 3 | 3 | 12 | 0.766 | 0.131 | <0.001 | <0.001 | – | – | |
| 2 Early-onset | 1 | 1 | 7 | 0.211 | 0.153 | 0.170 | – | 0.497 | – | |
| 3 Late-life | 3 | 3 | 9 | 0.334 | 0.121 | 0.006 | – | – | 0.003 | |
n, number of studies; s, number of samples; o, number of outcomes; g, Hedges' g; MDD, major depressive disorder; BD, bipolar disorder; τ, tau (estimate of the total standard deviation of the true effect size) for the interaction model including the moderators disorder and onset.