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. 2019 May 31;12:142. doi: 10.3389/fnmol.2019.00142

FIGURE 2.

FIGURE 2

2-arachidonoyl glycerol (2-AG) levels were upregulated relative to wild-type (WT) in most ABHD12 knockout (KO) brain areas, while age had minimal effects on 2-AG levels. Bar graphs show mean 2-AG levels in brain regions from young adult WT mice (WT young, light blue bars), young adult ABHD12 KO mice (KO young, light green bars), older adult WT mice (WT old, dark blue bars), and older adult ABHD12 KO mice (KO old, dark green bars). 2-AG concentrations are expressed in moles per gram of tissue. Error bars are ± standard error of the mean. ∗ indicates that means were significantly different in ABHD12 KO relative to WT mice of the same age at p < 0.05 whereas # indicates that means were significantly different in ABHD12 KO mice at p < 0.10. $ indicates that means were significantly different in older adults relative to younger adults of the same genotype at p < 0.05. Brain areas are striatum (STR), hippocampus (HIPP), cerebellum (CER), thalamus (THAL), cortex (CTX), hypothalamus (HYP), midbrain (MID), and brainstem (STEM).