Figure 11.

(A) Western blotting analysis of C. elegans JNK and MAP Kinase pathway specific proteins (p38, PDI-2, pJNK, caspases, RACK-1, HSP-1/90, and SGK) were performed. C. elegans exposed with E. coli OP50 and toxin proteins at 12, 24, and 48 h a pathway specific proteins were detected using the specific antibodies. The protein expression level at each time point was normalized to that of β-actin. PDI-2 is stress responsible protein which is found to assist in protein folding. (B). UniportKB protein-protein interaction showed close association and interaction between PMK-1(p38), RACK-1, PDI-2, HSF-1, and HSF-4 Proteins.