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. 2019 May 31;9:467. doi: 10.3389/fonc.2019.00467

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Copyright © 2019 Hiniker, Sodji, Quon, Gutkin, Arksey, Graves, Chin, Maxim, Diehn and Loo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative imaging of FDG-PET and FLT-PET in patients with equivocal follow-up FDG-PET scan after SABR to thoracic malignancy. (A) Patient #4 WITH disease recurrence predicted by FLT-PET and confirmed by progression on subsequent serial imaging (both SUV_maxlesion >2.0 and ratio SUV_max lesion and mediastinal blood pool >2.0) and focal FLT uptake. (B) Patient #8 WITHOUT disease recurrence predicted by FLT-PET and confirmed by biopsy (SUV_maxlesion >2.0 but ratio SUV_max lesion and mediastinal blood pool < 2.0). Equivocal lesion by FDG-PET highlighted by arrow ().

Inline graphic — Comparative imaging of FDG-PET and FLT-PET in patients with equivocal follow-up FDG-PET scan after SABR to thoracic malignancy. (A) Patient #4 WITH disease recurrence predicted by FLT-PET and confirmed by progression on subsequent serial imaging (both SUV_maxlesion >2.0 and ratio SUV_max lesion and mediastinal blood pool >2.0) and focal FLT uptake. (B) Patient #8 WITHOUT disease recurrence predicted by FLT-PET and confirmed by biopsy (SUV_maxlesion >2.0 but ratio SUV_max lesion and mediastinal blood pool < 2.0). Equivocal lesion by FDG-PET highlighted by arrow ().