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. 2019 May 21;12:121. doi: 10.3389/fnmol.2019.00121

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Copyright © 2019 Qu, Pan, He, Lang, Gao, Wang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evolutionary relationships of human Ras superfamily. The evolutionary history was inferred using the Neighbor-Joining method. After removing identical sequences, 162 amino acid sequences (Supplementary Table S1) are used for the analysis. All ambiguous positions were removed for each sequence pair. The original classification was indicated by different colors: Ras (lilac), Rho (cyan), Rab (purple), Arf (red), Ran (green), and Unclassified members (blank). Evolutionary analyses were conducted in MEGA7.