Table 2. Secondary cognitive and behavioral outcomes in MCI and AD.
Treatment | Groups | T0 | T1 | T2 | Within-group comparison (Time) |
Between-groups comparison (Treatment) |
|
FAB (0-18) |
PT | MCI AD |
12.9±2.5 8.9±2.4 |
13.4±3.6 9.9±2.4 |
12.7±3.5 8.5±2.8 |
||
CT | MCI AD |
11.7±2 8.6±1.9 |
12.8±2.7 9.1±2.3 |
12.7±3.1 7.7±2.9 |
AD: ✧ | ||
CTRL | MCI AD |
11.7±3 10.3±2.6 |
10.2±3.6 7.3±2.9 |
9.8±3.4 5.3±2.8 |
▲ ■ | ||
IADL (0-100%) |
PT | MCI AD |
88.2±23.6 56.2±35.1 |
86.4±22.1 50.5±32.9 |
81.8±21.2 39.2±31.2 |
||
CT | MCI AD |
84.1±19.8 58.5±28.8 |
89.5±18.8 54.1±29.8 |
86.1±19.6 38.2±26.6 |
■ | ||
CTRL | MCI AD |
84.4±25.9 48.9±23.4 |
73.1±34.3 34±25.5 |
56.4±33.8 21.1±18.3 |
■ ■ |
||
NPI (1-144) |
PT | MCI AD |
11.7±9.1 12.7±8.7 |
7±4.2 9.5±6.8 |
9.9±5.7 11±5.4 |
||
CT | MCI AD |
10.7±7.3 13.6±8.9 |
6±4.9 9.6±7.1 |
11.4±7.9 13.7±10.4 |
AD: ★✦☆✧ | ||
CTRL | MCI AD |
6.2±2.9 16.1±8.8 |
13.8±11.2 29.7±9.7 |
20.9±17.9 40±11.3 |
■ ▲ ■ |
Data are given as mean ± standard deviation. Abbreviations: PT: Physical Treatment group; CT: Cognitive Treatment group; CTRL: Control group; FAB: Frontal Assessment Battery; IADL: Instrumental Activity of Daily Living; NPI: Neuropsychiatric Inventory. T0: Pre-Treatment assessment; T1: Post-Treatment assessment; T2: Follow-p assessment.
Within-group (Time) comparison significant results (p ≤ 0.05): ▲ T0-T1; ■ T0-T2.
Between-groups (Treatment) significant results (p ≤ 0.05): ★ T1 PT vs T1 CTRL; ✦ T1 CT vs T1 CTRL; ☆ T2 PT vs T2 CTRL; ✧ T2 CT vs T2 CTRL.