Table 2. The risk effect of comorbidities on fatal outcome in SFTS patients.
| Outcome | ||||||
|---|---|---|---|---|---|---|
| Fatal | Survival | OR(95%CI) | P value | Adjusted | Adjusted | |
| OR(95%CI)# | P value# | |||||
| Without comorbidities | 165 (12.5) | 1152 (87.5) | Reference | Reference | ||
| One kind of comorbidity | 123 (22.0) | 436 (78.0) | 1.970 (1.521–2.550) | <0.001 | 1.631 (1.233–2.159) | <0.001 |
| Hyperlipidemia | 19 (13.2) | 125 (86.8) | 1.061 (0.638–1.766) | 0.819 | 0.912 (0.520–1.601) | 0.749 |
| Hypertension | 24 (21.2) | 89 (78.8) | 1.883 (1.166–3.041) | 0.010* | 1.610 (0.956–2.710) | 0.073 |
| Chronic viral hepatitis | 26 (21.3) | 96 (78.7) | 1.891 (1.190–3.004) | 0.007* | 2.006 (1.215–3.311) | 0.007* |
| Diabetes | 18 (27.7) | 47 (72.3) | 2.674 (1.516–4.715) | 0.001* | 2.462 (1.310–4.630) | 0.005* |
| COPD | 16 (44.4) | 20 (55.6) | 5.585 (2.837–10.996) | <0.001 | 2.715 (1.295–5.691) | 0.008* |
| Two kinds of comorbidities | 40 (22.4) | 139 (77.6) | 2.009 (1.363–2.961) | <0.001 | 1.447 (0.955–2.194) | 0.082 |
| Hypertension & Hyperlipidemia | 7 (26.9) | 19 (73.1) | 2.572 (1.065–6.213) | 0.036* | 2.101 (0.822–5.370) | 0.121 |
| Diabetes & Hyperlipidemia | 7 (38.9) | 11 (61.1) | 4.443 (1.699–11.622) | 0.002* | 3.545 (1.184–10.620) | 0.024* |
| Chronic viral hepatitis & Hyperlipidemia | 1 (5.3) | 18 (94.7) | 0.388 (0.051–2.925) | 0.358 | 0.309 (0.040–2.409) | 0.262 |
| Chronic viral hepatitis & Hypertension | 3 (20.0) | 12 (80.0) | 1.745 (0.487–6.250) | 0.392 | 1.010 (0.257–3.975) | 0.989 |
| Diabetes & Hypertension | 2 (12.5) | 14 (87.5) | 0.997 (0.225–4.428) | 0.997 | 0.921 (0.198–4.287) | 0.917 |
| Diabetes & Chronic viral hepatitis | 5 (45.5) | 6 (54.5) | 5.818 (1.756–19.278) | 0.004* | 4.792 (1.345–17.077) | 0.016* |
| Three or more kinds of comorbidities | 12 (29.3) | 29 (70.7) | 2.889 (1.446–5.773) | 0.003* | 2.399 (1.128–5.106) | 0.023* |
#Adjusting for age, sex, time from disease onset to admission and treatment regimens (ribavirin, corticosteroid and immunoglobulin) by applying logistic regression model. The COPD was not listed in the two kinds of comorbidities due to the small sample size.
* P < 0.05.