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. 2019 May;112(5):649–705. doi: 10.5935/abc.20190086
2nd Challenge: summary of challenges regarding approach individualization
Heterogeneous population
Moderate to high risk in the most utilized risk stratification scores (TIMI, GRACE)
Treatment should consider overall health, comorbidities, cognitive status, life expectancy, frailty, patient's wishes and preferences
It is necessary to pay attention to pharmacokinetic alterations and sensitivity to hypotensive drugs