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Oxidative stress and enzymatic antioxidant defense system in diabetic renal cells. CAT: catalase; ROS: reactive oxygen species; GPx: glutathione peroxidase; GSH: glutathione; GSSG: oxidized glutathione; RG: reduced glutathione; H2O2: hydrogen peroxide; NRF2: nuclear erythroid 2-related factor 2; O2: molecular oxygen; NOX: NADPH oxidase; O2•-: superoxide anion radical; •OH: hydroxyl radical; SOD: superoxide dismutase. Adapted from Bhargava.
