Table 2.
Clinicopathological features related to EBV expression
| EBV-positive, n=13 (6%) | EBV-negative, n=196 (94%) | P value | |
| Characteristics | |||
| Median age (range) | 66.7 (38–87) | 69.9 (64–95) | 0.47* |
| Gender, n (%) | |||
| Female | 3 (23) | 69 (35) | 0.37† |
| Male | 10 (77) | 127 (65) | |
| Location, n (%) | |||
| GEJ and cardia | 8 (62) | 43 (22) | 0.005† |
| Body and antrum | 5 (38) | 147 (75) | |
| Gastric pouch | 0 | 6 (3) | |
| Lauren histological classification, n (%) | |||
| Intestinal | 10 (77) | 120 (61.2) | 0.52† |
| Diffuse | 2 (15.3) | 50 (25.51) | |
| Mixed | 1 (7.7) | 26 (13.27) | |
| Tumour location-modified Lauren classification, n (%) | |||
| PND | 7 (54) | 33 (16.8) | 0.01† |
| D | 3 (23) | 76 (38.8) | |
| DND | 3 (23) | 87 (44.4) | |
| pTNM stage, n (%) | |||
| I | 1 (8.3) | 37 (22.4) | 0.66† |
| II | 5 (41.6) | 49 (29.7) | |
| III | 5 (41.6) | 65 (39.4) | |
| IV | 1 (8.3) | 14 (8.5) | |
| pN stage, n (%) | |||
| N0 | 4 (33.3) | 66 (40) | 0.73† |
| N1 | 3 (25) | 30 (18.2) | |
| N2 | 2 (16.7) | 30 (18.2) | |
| N3 | 3 (25) | 39 (23.6) | |
| Lymphovascular invasion, n (%) | |||
| Absent | 8 (62) | 71 (36.4) | 0.11† |
| Present | 4 (38) | 94 (35.4) | |
Significant p-values are shown in bold
*Wilcoxon test.
†Fisher’s exact test.
D, diffuse; DND, distal non-diffuse; EBV, Epstein-Barr virus; GEJ, gastro-oesophageal junction; PND, proximal non-diffuse; pN, pathological N; pTNM, pathological TNM.