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. Author manuscript; available in PMC: 2020 May 28.
Published in final edited form as: Biomater Sci. 2019 May 28;7(6):2326–2334. doi: 10.1039/c9bm00020h

Fig. 7.

Fig. 7

In vivo osteogenesis induced by differently treated SF films. Immunohistochemical staining of Col I, OPN and OCN in the subcutaneously implanted SF, A-SF, SF-nHAp and A-SF-nHAp films seeded with MSCs. Blue and red arrows indicated the positive expression of OPN and OCN, respectively. Immunohistochemical staining showed that more bone matrix proteins were deposited around the A-SF and A-SF-nHAp films than around the SF and SF-HAp films. Moreover, more OPN was deposited around the A-SF-nHAp than around A-SF films. SF: pristine SF film; A-SF: air-plasma-treated SF film; SF-nHAp: SF film with mineralized nHAp; A-SF-nHAp: A-SF film with mineralized nHAp; M: implanted materials.