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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: J Neurosurg Anesthesiol. 2019 Oct;31(4):385–391. doi: 10.1097/ANA.0000000000000566

Table 1.

Baseline characteristics and postoperative delirium (univariate analysis)

Postoperative Delirium Status

Total n = 715 (%) Yes n = 127 (17.8) No n = 588 (82.2) P-value
Preoperative variables
Age, years, mean ± SD 73.6 ± 6.0 75.0 ± 6.6 73.3 ± 5.9 0.0051
Male, n (%) 351 (49.1) 60 (47.2) 292 (49.5) 0.6462
Baseline living situation, n (%), n = 648
 Independent 619 (95.5) 115 (92.0) 504 (96.4)
 Nursing home/ Facility 29 (4.5) 10 (8.0) 19 (3.6) 0.0342
Marital status, n (%), n = 705
 Married / Partner 490 (69.5) 85 (68.0) 405 (69.8)
 Other 215 (30.5) 40 (32.0) 175 (30.2) 0.6872
Body mass index, Kg/m2, mean ± SD, n = 706 29.0 (5.5) 29.2 (6.1) 28.9 (5.4) 0.5911
ASA physical status, n (%)
 < 3 243 (34.0) 18 (14.2) 225 (38.3)
 ≥ 3 472 (66.0) 109 (85.8) 363 (61.7) <0.0012
Metabolic Equivalents of Task, n (%), n = 612
 < 4 169 (27.6) 44 (46.8) 125 (24.1)
 ≥ 4 443 (72.4) 50 (53.2) 393 (75.9) <0.0012
Depression, n (%), n = 701
 No 461 (65.8) 61 (49.6) 400 (69.2)
 Yes 240 (34.2) 62 (50.4) 178 (30.8) <0.0012
Anxiety, n (%), n = 703
 No 512 (72.8) 78 (63.4) 434 (74.8)
 Yes 191 (27.2) 45 (36.6) 146 (25.2) 0.0102
Total number of medications median [25th-75th], n = 712 7 [5–11] 8 [6–12] 7 [5–11] 0.0023
Preoperative opioid use, n (%), n = 712
 No 449 (63.1) 65 (51.6) 384 (65.5)
 Yes 263 (36.9) 61 (48.4) 202 (34.5) 0.0032
Number of past previous surgeries median [25th-75th], n = 664 4 [2–6] 4 [2–7] 4 [2–6] 0.2753
Case classification, n (%), n = 710
 Elective 655 (92.3) 98 (79.0) 557 (95.1)
 Non-elective 55 (7.8) 26 (21.0) 29 (5.0) <0.0012

SD: standard deviation, ASA: American Society of Anesthesiologists physical status

1

T-tests were used.

2

Chi-square tests were used

3

Wilcoxon rank sum tests were used

4

Fisher’s exact tests were used