Skip to main content
. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: J Mol Cell Cardiol. 2019 Mar 22;130:49–58. doi: 10.1016/j.yjmcc.2019.03.015

Figure 1.

Figure 1

Cardiomyocyte specific ADK disruption causes spontaneous LV hypertrophy. (A) Tamoxifen induced cardiomyocyte specific excision of floxed exon 7 in the ADK gene. (B) 4 weeks after the last tamoxifen injection, ADK protein expression was eliminated specifically in heart muscle in cADK−/− mice. (C) Heart weight to body weight ratio of cADK−/− and WT mice (n=9 WT and 10 cADK−/− ). (D, E) β-MHC expression in WT and cADK−/− was analyzed by western blot (n=4 WT and 4 ADK−/−).