Table 2.
Adverse events during first and rechallenged sunitinib treatment
| Adverse events | First sunitinib N (%) | Rechallenged sunitinib N (%) | ||
|---|---|---|---|---|
| Grade 1/2 | Grade 3/4 | Grade 1/2 | Grade 3/4 | |
| Diarrhea | 12 (57) | 13 (62) | ||
| Hypothyreosis | 12 (57) | 14 (67) | ||
| Hypertension | 12 (57) | 10 (48) | ||
| Anemia | 11 (52) | 16 (76) | ||
| Mucositis | 9 (43) | 9 (43) | ||
| Thrombocytopenia | 5 (24) | 3 (14) | 8 (38) | 2 (10) |
| Renal toxicity | 7 (33) | 1 (5) | 6 (29) | 1 (5) |
| Hand-foot syndrome | 6 (29) | 5 (24) | ||
| Vomiting | 5 (24) | 3 (14) | ||
| Hepatic toxicity | 5 (24) | 3 (14) | ||
| Leucopenia | 3 (14) | 8 (38) | ||
| Cardiovascular toxicity | 1 (5) | |||
| Other | 5 (24) | 2 (10) | 2 (10) | 1 (5) |