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. 2019 Jun 7;9:8354. doi: 10.1038/s41598-019-44590-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Heatmap depicting the top 20 metabolites differently abundant between Pregnant and Control ULF samples based on P-values. (B) Quantitative Enrichment Analysis highlighted the metabolic pathways that were enriched in the Pregnant compared to the Control group, using the MetaboAnalyst 4.0 functional interpretation tools. The horizontal bars summarize the main metabolite sets identified in this analysis; the bars are coloured based on their P-values and the length is based on the -fold enrichment.