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. 2019 Jun 7;7(11):e14140. doi: 10.14814/phy2.14140

Table 1.

Group‐averaged means (with SD) of measures

Measures Baseline (n = 18) 6 Weeks (n = 18) Paired t‐test and effect size
VO2peak 34.9 ± 4.6 39.3 ± 5.0 P  < 0.001, d  = 0.894
AUCRest Sqrt Transform 2.19 ± 0.51 2.11 ± 0.60 P = 0.541, d = 0.144
AUCActive 8.54 ± 3.46 8.59 ± 2.77 P = 0.933, d = 0.016
ICF 1.30 ± 0.27 1.15 ± 0.19 P  = 0.048, d = 0.656
SICI 0.52 ± 0.25 0.50 ± 0.20 P = 0.752, d = 0.088
BDNF Sqrt Transform 4.21 ± 1.06 4.37 ± 0.95 P = 0.549, d = 0.159
IGF‐1 160.90 ± 41.15 154.50 ± 35.10 P = 0.198, d = 0.167
Total CTSB 30.32 ± 12.17 31.77 ± 11.85 P = 0.133, d = 0.121
Pro‐CTSB 15.39 ± 6.45 15.93 ± 6.72 P = 0.391, d = 0.082
OSPAN 49.67 ± 13.51 53.11 ± 11.57 P = 0.142, d = 0.274

AUC, area under the curve; BDNF, brain‐derived neurotrophic factor; CTSB, cathepsin B; ICF, intracortical facilitation; IGF‐1, insulin‐like growth factor 1; OSPAN, operation span task; SICI, short‐interval intracortical inhibition; VO2peak, peak oxygen uptake. Bold font indicates statistical significance.