Figure 2.

The effects of exosomes (EXO) on BLM‐induced lung inflammation, with or without serelaxin (RLX). Representative images of H&E‐stained lung sections from mice subjected to BLM‐induced pulmonary fibrosis and the various treatment strategies investigated (a) demonstrate the extent of interstitial lung inflammation. Scale bar = 80 μm. Also shown is the mean ± SEM BLM‐induced interstitial inflammation score (b), neutrophil counts (c), and macrophage counts (d) from 5 to 6 fields per mouse section; n = 7 animals per group. *P < 0.05, significantly different from the control group (SAL); ^# P < 0.05, significantly different from the BLM‐treated injured group; ^¶ P < 0.05, significantly different from the BLM + 5‐μg EXO‐treated group; ^† P < 0.05, significantly different from theBLM + 25‐μg EXO‐treated group; ^§ P < 0.05, significantly different from the BLM + RLX‐treated group