Table 2.
Associations between MMR status and selected clinicopathological characteristics, in the entire cohort.
| Colorectal cancer (N=991) | Endometrial cancer (N=167) | |||||
| dMMR | pMMR | P value | dMMR | pMMR | P value | |
| Age | < 0.001 | 0.539 | ||||
| N | 114 | 874 | 80 | 87 | ||
| Median | 61.1 | 64.9 | 64.6 | 63.8 | ||
| Range | (23.7–81.5) | (20.5–79.5) | (35.4–87.2) | (35.1–85.1) | ||
| Grade | < 0.001 | 0.025 | ||||
| 1 | 7 (6.4) | 70 (8.2) | 31 (38.8) | 17 (20.0) | ||
| 2 | 69 (62.7) | 656 (76.7) | 33 (41.3) | 42 (49.4) | ||
| 3 | 34 (30.9) | 129 (15.1) | 16 (20.0) | 26 (30.6) | ||
| Primary tumour (T) | 0.369 | 0.234 | ||||
| T1 | 0 (0) | 4 (0.5) | 65 (84.4) | 64 (76.2) | ||
| T2 | 6 (5.4) | 73 (8.6) | 6 (7.8) | 6 (7.1) | ||
| T3 | 94 (84.7) | 712 (84.2) | 6 (7.8) | 14 (16.7) | ||
| T4 | 11 (9.9) | 57 (6.7) | ||||
| Regional lymph nodes (N) | < 0.001 | 0.507 | ||||
| N0 | 71 (63.4) | 337 (39.6) | 65 (89.0) | 60 (88.2) | ||
| N1 | 27 (24.1) | 343 (40.3) | 5 (6.8) | 7 (10.3) | ||
| N2 | 14 (12.5) | 172 (20.2) | 3 (4.1) | 1 (1.5) | ||
| Stage | < 0.001 | 0.425 | ||||
| I | 3 (2.7) | 5 (0.6) | 61 (79.2) | 59 (70.2) | ||
| II | 68 (60.7) | 337 (38.7) | 4 (5.2) | 6 (7.1) | ||
| III | 41 (36.6) | 530 (60.8) | 12 (15.6) | 19 (22.6) | ||
| Radiation therapy | < 0.001 | 0.244 | ||||
| No | 94 (87.9) | 563 (70.6) | 27 (33.8) | 37 (42.5) | ||
| Yes | 13 (12.1) | 234 (29.4) | 53 (66.3) | 50 (57.5) | ||
.N, number; dMMR, mismatch repair deficient; pMMR, mismatch repair proficient.