Table 6.
Association of human leukocyte antigen (HLA) haplotypes with expanded disability status scale (EDSS) in patients with multiple sclerosis (MS) in Khuzestan, Iran
| HLA haplotypes |
Positive haplotype
|
Total
|
P | ||
|---|---|---|---|---|---|
|
EDSS (1-4.5)
|
EDSS (5-10)
|
EDSS (1-4.5)
|
EDSS (5-10)
|
||
| n (%) | n (%) | n (%) | n (%) | ||
| DRB1*1501+-DRB5*01+ | 22 (13.58) | 1 (12.50) | 162 | 8 | 0.931 |
| DRB1*1501--DRB5*01- | 67 (40.85) | 2 (33.33) | 164 | 6 | 0.713 |
| DRB1*1501+-DRB5*01- | 42 (25.76) | 5 (62.50) | 163 | 8 | 0.026* |
| DRB1*1501--DRB5*01+ | 25 (15.92) | 0 (0) | 157 | 8 | 0.220 |
HLA: Human leukocyte antigen; EDSS: Expanded disability status scale
*
Significant P-values; statistical significance was at P < 0.050.