Table 2.
Quantitative MR parameters.
| Groups | RRMS | PMS | HC |
|---|---|---|---|
| Scanner 1/Scanner 2 | 11/4 | 15/6 | 11/25 |
| Volumetric Data, %, mean (SD) | |||
| BPF | 84.99 (2.02) | 83.67 (2.47)b | 85.39 (1.75) |
| GMF | 51.06 (2.11) | 48.49 (3.16)b | 52.76 (1.99) |
| Lesion F | 1.21 (0.98)a | 2.26 (1.50) | N/A |
| Median MPM values, mean (SD) | |||
| MT (p.u) | |||
| NACGM | 0.71 (0.09)c | 0.68 (0.09)b | 0.82 (0.09) |
| NADGM | 0.91 (0.12) | 0.83 (0.10)b | 0.98 (1.13) |
| NAWM | 1.49 (0.18)c | 1.45 (0.16)b | 1.68 (0.14) |
| Lesion | 0.96 (0.26) | 0.89 (0.24) | N/A |
| R2* (Hz) | |||
| NACGM | 15.20 (1.19)c | 15.35 (1.17)b | 16.62 (1.02) |
| NADGM | 20.74 (2.63) | 22.46 (2.94) | 22.04 (3.10) |
| NAWM | 20.08 (1.34)c | 20.24 (1.27)b | 21.60 (1.03) |
| Lesion | 15.03 (2.23) | 14.51 (2.30) | N/A |
| R1 (Hz) | |||
| NACGM | 0.62 (0.02)c | 0.61 (0.03)b | 0.64 (0.02) |
| NADGM | 0.75 (0.05) | 0.75 (0.05) | 0.77 (0.06) |
| NAWM | 0.99 (0.05)c | 0.99 (0.05)b | 1.04 (0.03) |
| Lesion | 0.78 (0.12) | 0.75 (0.10) | N/A |
Abbreviations: BPF = brain parenchymal fraction, GMF = grey matter fraction, Lesion F = lesion fraction, NACGM = normal appearing cortical grey matter, NADGM = normal appearing deep grey matter, NAWM = normal appearing white matter, N/A = not applicable.
a
Difference between RRMS and PMS statistically significant (alpha value of 0.05).
b
Difference between PMS and HC statistically significant (alpha value of 0.05).
c
Difference between RRMS and HC statistically significant (alpha value of 0.05).