Table 1.
Subject Characteristics
| Infrequent Exacerbator | Frequent Exacerbator | p value* | |
|---|---|---|---|
| N | 11 | 11 | |
| Sex, Male (%) | 11 (100) | 11 (100) | |
| Age, mean (sd) | 68.36 (5.45) | 70.82 (7.12) | 0.39 |
| Race, white (%) | 11 (100) | 10 (90.9) | 1.00 |
| BMI, mean (sd) | 29.25 (6.01) | 26.09 (6.85) | 0.26 |
| Hypertension, Yes (%) | 6 (54.5) | 6 (54.5) | 1.00 |
| Diabetes, Yes (%) | 2 (18.2) | 3 (27.3) | 1.00 |
| COPD Severity (%) | |||
| Moderate | 5 (45.5) | 3 (27.3) | |
| Severe | 4 (36.4) | 3 (27.3) | |
| Very Severe | 2 (18.2) | 5 (45.5) | |
| FEV1% predicted | 46.82 (13.93) | 35.5 (15.18) | 0.088 |
| COPD exacerbations in the last 12 months, mean (sd) | 0 (0) | 2.91 (1.04) | < 0.001 |
| COPD hospitalizations in the last 12 months, mean (sd) | 0 (0) | 0.55 (0.69) | 0.035 |
| Inhaled corticosteroid use, Yes (%) | 6 (54.5) | 7 (63.6) | 1.00 |
| Pack-years of smoking, mean (sd) | 61.18 (31.94) | 69.55 (48.57) | 0.66 |
| Current tobacco use, Yes (%) | 5 (45.5) | 3 (27.3) | 0.66 |
| Current alcohol use, Yes (%) | 7 (63.6) | 9 (81.8) | 0.64 |
| Brush teeth ≥ once daily (%) | 9 (81.8) | 10 (90.9) | 1.00 |
| History of periodontal disease, Yes (%) | 3 (27.3) | 2 (18.2) | 1.00 |
| SGRQ Score, mean (sd) | 49.72 (7.92) | 48.27 (16.20) | 0.792 |
BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1% predicted, forced expiratory volume in 1 s, percent of predicted value; sd, standard deviation; SGRQ, St. George’s Respiratory Questionnaire
*A Fisher-Pitman permutation test was conducted for all continuous variables and a Fishers exact test for all categorical variables